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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1974 2
1983 1
1985 2
1990 1
1992 1
1994 1
1995 1
1996 1
1997 1
2000 2
2001 2
2002 1
2003 2
2004 3
2005 1
2006 3
2007 7
2008 4
2009 1
2010 1
2011 3
2012 5
2013 6
2014 2
2015 6
2016 1
2017 3
2018 3
2020 2
2021 3
2022 4
2024 0

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73 results

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Page 1
Kenyan and Ethiopian distance runners: what makes them so good?
Wilber RL, Pitsiladis YP. Wilber RL, et al. Int J Sports Physiol Perform. 2012 Jun;7(2):92-102. doi: 10.1123/ijspp.7.2.92. Int J Sports Physiol Perform. 2012. PMID: 22634972 Review.
Several factors have been proposed to explain the extraordinary success of the Kenyan and Ethiopian distance runners, including (1) genetic predisposition, (2) development of a high maximal oxygen uptake as a result of extensive walking and running at an early age, (3) rel …
Several factors have been proposed to explain the extraordinary success of the Kenyan and Ethiopian distance runners, including (1) genetic …
Human adaptation to high altitude: a review of convergence between genomic and proteomic signatures.
Sharma V, Varshney R, Sethy NK. Sharma V, et al. Hum Genomics. 2022 Jul 15;16(1):21. doi: 10.1186/s40246-022-00395-y. Hum Genomics. 2022. PMID: 35841113 Free PMC article. Review.
Both genomics- and proteomics-based investigations have identified several essential genes, proteins, and pathways that may facilitate human adaptive genotype/phenotype in a population-specific manner. This comprehensive review provides an up-to-date list of genes and prot …
Both genomics- and proteomics-based investigations have identified several essential genes, proteins, and pathways that may facilitate human …
Measuring high-altitude adaptation.
Moore LG. Moore LG. J Appl Physiol (1985). 2017 Nov 1;123(5):1371-1385. doi: 10.1152/japplphysiol.00321.2017. Epub 2017 Aug 31. J Appl Physiol (1985). 2017. PMID: 28860167 Free PMC article. Review.
High altitudes (>8,000 ft or 2,500 m) provide an experiment of nature for measuring adaptation and the physiological processes involved. Studies conducted over the past ~25 years in Andeans, Tibetans, and, less often, Ethiopians show varied but distinct O( …
High altitudes (>8,000 ft or 2,500 m) provide an experiment of nature for measuring adaptation and the physiological …
High-Altitude Adaptation: Mechanistic Insights from Integrated Genomics and Physiology.
Storz JF. Storz JF. Mol Biol Evol. 2021 Jun 25;38(7):2677-2691. doi: 10.1093/molbev/msab064. Mol Biol Evol. 2021. PMID: 33751123 Free PMC article. Review.
Population genomic analyses of high-altitude humans and other vertebrates have identified numerous candidate genes for hypoxia adaptation, and the physiological pathways implicated by such analyses suggest testable hypotheses about underlying mechanisms. ...S …
Population genomic analyses of high-altitude humans and other vertebrates have identified numerous candidate genes for hypoxia …
Iron metabolism in high-altitude residents.
Muckenthaler MU, Mairbäurl H, Gassmann M. Muckenthaler MU, et al. J Appl Physiol (1985). 2020 Oct 1;129(4):920-925. doi: 10.1152/japplphysiol.00019.2020. Epub 2020 Aug 27. J Appl Physiol (1985). 2020. PMID: 32853112 Free article. Review.
The increase in hemoglobin levels requires high amounts of additional iron supplied from the diet. Here, we review available data on how iron metabolism adapts when living in a hypoxic environment. Our analysis reveals that long-term adaptation to h …
The increase in hemoglobin levels requires high amounts of additional iron supplied from the diet. Here, we review available d …
High Altitude Pulmonary Hypertension.
Bussotti M, Marchese G. Bussotti M, et al. Cardiovasc Hematol Disord Drug Targets. 2018;18(3):187-198. doi: 10.2174/1871529X18666180518085245. Cardiovasc Hematol Disord Drug Targets. 2018. PMID: 29773069 Review.
The effects of hypoxia were simulated in laboratory by means of an induced low pressure environment (normobaric hypoxia) or tested on the subjects at different levels of altitude (hypobaric hypoxia). Far from describing all the physiological and pathological responses of t …
The effects of hypoxia were simulated in laboratory by means of an induced low pressure environment (normobaric hypoxia) or tested on the su …
Altitude acclimatization, hemoglobin-oxygen affinity, and circulatory oxygen transport in hypoxia.
Storz JF, Bautista NM. Storz JF, et al. Mol Aspects Med. 2022 Apr;84:101052. doi: 10.1016/j.mam.2021.101052. Epub 2021 Dec 5. Mol Aspects Med. 2022. PMID: 34879970 Free PMC article. Review.
In mammals and other air-breathing vertebrates that live at high altitude, adjustments in convective O(2) transport via changes in blood hemoglobin (Hb) content and/or Hb-O(2) affinity can potentially mitigate the effects of arterial hypoxemia. However, there …
In mammals and other air-breathing vertebrates that live at high altitude, adjustments in convective O(2) transport via change …
Ventilatory and cerebrovascular regulation and integration at high-altitude.
Hoiland RL, Howe CA, Coombs GB, Ainslie PN. Hoiland RL, et al. Clin Auton Res. 2018 Aug;28(4):423-435. doi: 10.1007/s10286-018-0522-2. Epub 2018 Mar 24. Clin Auton Res. 2018. PMID: 29574504 Review.
Ascent to high-altitude elicits compensatory physiological adaptations in order to improve oxygenation throughout the body. ...Simultaneously, cerebral blood flow increases during initial exposure to altitude when hypoxemia is the greatest. Following v …
Ascent to high-altitude elicits compensatory physiological adaptations in order to improve oxygenation throughout the b …
Ethiopian Native Highlander's Adaptation to Chronic High-Altitude Hypoxia.
Getu A. Getu A. Biomed Res Int. 2022 Apr 15;2022:5749382. doi: 10.1155/2022/5749382. eCollection 2022. Biomed Res Int. 2022. PMID: 35463974 Free PMC article. Review.
People living in a high-altitude environment have distinct lifelong challenges. Adaptive mechanisms have allowed high-altitude residents to survive in a low-oxygen environment for thousands of years. The purpose of this review was to provide a b …
People living in a high-altitude environment have distinct lifelong challenges. Adaptive mechanisms have allowed hig …
[Hemoglobin and testosterone: importance on high altitude acclimatization and adaptation].
Gonzales GF. Gonzales GF. Rev Peru Med Exp Salud Publica. 2011 Mar;28(1):92-100. doi: 10.1590/s1726-46342011000100015. Rev Peru Med Exp Salud Publica. 2011. PMID: 21537776 Free article. Review. Spanish.
Acclimatization is observed in individuals temporarily exposed to high altitude, and to some extent, it enables them to tolerate the high altitudes. ...Adaptation is the process of natural acclimatization where genetical variations …
Acclimatization is observed in individuals temporarily exposed to high altitude, and to some extent, it enables them to …
73 results